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Vitamin C Trialed As Life-Saving Treatment For Intensive Care Patients With Sepsis

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NEWS

Researchers at the University of Otago in Christchurch, New Zealand are teaming up with intensive care specialists to study whether intravenous infusions of vitamin C could be a life-saving treatment for patients with sepsis.

COMMENT

The plans for this study build on work carried out by Dr. Paul E. Marik, an intensive-care physician at the Eastern Virginia Medical School in Norfolk, Virginia, in the United States. Responsible for the deaths of up to 8 million people globally each year, sepsis is currently the leading cause of death among hospitalized patients.

In a study published in the journal Chest in 2017, Dr. Marik and colleagues describe how, based on the use of an intravenous combination of vitamin C, vitamin B1, and the hormone hydrocortisone, their approach saw just 4 deaths among the 47 patients who received it.

Pointing out in another paper that around 40 percent of ICU patients with septic shock have extremely low serum levels of vitamin C consistent with a diagnosis of scurvy, and that the remainder of sepsis patients similarly have insufficient levels, Dr. Marik explains how the clinical benefit of vitamin C in these conditions is synergistically enhanced by the inclusion of vitamin B1 and low-dose corticosteroids. Noting how most clinicians are unaware that primates and guinea pigs are the only mammals that are unable to synthesize vitamin C in their bodies, he says the inability to generate their own vitamin C makes humans very susceptible to dysfunction in a variety of biochemical pathways that are vital for surviving a critical illness such as sepsis. Clearly, the ideas behind this work bear numerous parallels to the pioneering scientific research of Dr. Rath.

To learn more about Dr. Marik’s work, we recommend reading a fascinating interview with him that we recently published on our website.

Read article at medicalxpress.com

1 Comment

  1. John says:

    Its truly heartbreaking that Sepsis remains the third leading cause of death when a cure was announced a year ago. The Marik Protocol represents a real breakthrough, offering safe, effective, affordable adjunct therapy for Sepsis with a remarkable reduction in Death rate. So why the widespread skepticism, reluctance to implement this therapy on a trial basis ? Besides the wide spread bias in the Medical Community favoring prescription drug therapy ( this therapy relies on natural metabolites ), there is the money involved in treating Sepsis. Sepsis patients represent a group that stays in the Hospitals longer, and with more repeat visits. Hospital administrators make more money off of Sepsis patients, and have little to gain by a therapy that sends patients home quickly, having attained a more robust recovery. Organizations like Sepsis Alliance, which has a critical view of the Marik Protocol likewise have everything to loose from an affordable cure. They never reveal their conflicts of interest when they offer their critical opinions.
    Meanwhile, patients are not offered a choice of treatments, and death by Septic Shock remains a leading killer, with 8 million deaths yearly world wide, a genocidal rate of mortality considering a cure is being ignored.
    Need Convincing ? Listen to what the ICU nurses who have witness the healing of the Marik Protocol have to say: ICU nurses discuss vitamin C therapy for sepsis

    See Cost of Sepsis: https://blogs.cdc.gov/safehealthcare/the-cost-of-sepsis, see Scepticaemia: The impact on the health system and patients of delaying new treatments with uncertain evidence; a case study of the sepsis bundle [version 1; referees: 1 approved] , https://f1000research.com/articles/7-500/v1,

    Another relevant issue is the ethics of conducting a double blind RCT, l when the outcome of the controls is 30 to 40 percent mortality. All to better substantiate the cure rate. Better wide spread trial adoption of the Merick Protocol, or at least give patients an option to choose this therapy.
    I have no conflicts of interest in this issue.

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