A new clinical trial at Emory University and 45 other sites around the United States will test a combination of vitamins and steroids in patients diagnosed with sepsis.
Caused by the body’s overwhelming response to infection, sepsis can lead to tissue damage, organ failure and death. Responsible for the deaths of up to 8 million people globally each year, it is the leading cause of mortality among hospitalized patients.
The specific sepsis treatment that will be tested in the new clinical trial was originally developed by Dr. Paul E. Marik, an intensive-care unit physician at the Eastern Virginia Medical School in the United States. In a study published in the journal Chest in 2017, Dr. Marik and colleagues described how, based on the use of an intravenous combination of vitamin C, vitamin B1, and the hormone hydrocortisone, their approach saw just 4 deaths from 47 patients. An inspiring video featuring nurses who have administered the treatment recounts how it has proved so effective that dying patients improve within 12 hours and go on to make full recoveries.
You can learn more about this approach to sepsis in a fascinating interview with Dr. Marik on our website.