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Researchers Propose L-Arginine Blend To Restore Performance And Relieve Long Covid

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L-arginine combined with vitamin C can improve physical performance, muscle strength, endothelial function, and fatigue in adults with long Covid and should be considered a treatment option to relieve persistent symptoms, according to a study published in the journal Nutrients. [Source:]


Because of its immune modulating properties, vitamin C has become recognized as the critical nutrient in the COVID-19 pandemic. Combining it with the amino acid arginine takes advantage of the principle of nutrient synergy.

A systematic review published in 2021 in the journal Nutrients examined the feasibility of using high-dose intravenous (IV) vitamin C in the treatment of post-viral fatigue and ‘long COVID’. Reviewing 9 clinical studies involving a total of 720 participants, the authors found that treatment with vitamin C resulted in a significant reduction in fatigue. Other symptoms such as sleep disturbances, lack of concentration, depression, and pain were also frequently alleviated.

Noting that vitamin C deficiency has been demonstrated in COVID-19 and other acute severe infections, the Nutrients review authors proposed that high-dose IV administration of this vital nutrient may be a suitable treatment option for patients afflicted with these conditions.

With a UK survey suggesting about one in five people have symptoms of long COVID five weeks after an initial coronavirus infection, and one in seven after twelve weeks, there is clearly a need for effective, safe treatment options to be found. If used alongside a science-based combination of synergistic micronutrients, it is clear that high-dose vitamin C has remarkable potential to improve patients’ quality of life.

To learn more about the use of high-dose vitamin C to treat post-viral fatigue and long COVID, see this article on our website.

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