This study analyzed data from 28,621 adults aged 20 to 80 years in the United States National Health and Nutrition Examination Survey and assessed them using a magnesium depletion score (MgDS). It discovered that for each one-point increase in the MgDS, the odds of having an overactive bladder rose by 9 percent.
People with moderate or high magnesium depletion were more likely to experience overactive bladder symptoms compared to those with low depletion. The effect was particularly strong in women, nonsmokers, middle-aged adults, and people with obesity, suggesting certain groups may be more vulnerable to the impact of low magnesium.
The researchers concluded that magnesium depletion may play a role in the development of an overactive bladder and that this relationship remained strong even after accounting for other health and lifestyle factors. They suggest that magnesium status could be an important factor to consider in both the prevention and management of bladder health problems.
To read how new evidence links magnesium deficiency to major neurological disorders, see this article on our website.
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September 26, 2025Magnesium Depletion Linked to Increased Overactive Bladder Risk
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Magnesium depletion is associated with an increased risk for overactive bladder, according to a study published online in the journal Scientific Reports.
[Source: medicalxpress.com]
[Image source: Adobe Stock]
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This study analyzed data from 28,621 adults aged 20 to 80 years in the United States National Health and Nutrition Examination Survey and assessed them using a magnesium depletion score (MgDS). It discovered that for each one-point increase in the MgDS, the odds of having an overactive bladder rose by 9 percent.
People with moderate or high magnesium depletion were more likely to experience overactive bladder symptoms compared to those with low depletion. The effect was particularly strong in women, nonsmokers, middle-aged adults, and people with obesity, suggesting certain groups may be more vulnerable to the impact of low magnesium.
The researchers concluded that magnesium depletion may play a role in the development of an overactive bladder and that this relationship remained strong even after accounting for other health and lifestyle factors. They suggest that magnesium status could be an important factor to consider in both the prevention and management of bladder health problems.
To read how new evidence links magnesium deficiency to major neurological disorders, see this article on our website.
Dr. Rath Health Foundation
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