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New Review Highlights Significant Benefits Of Vitamin And Mineral Supplements For Reducing Fatigue


A new literature review from Australian and UK authors suggests vitamins and minerals have “potentially significant benefits” in reducing fatigue both in healthy people and those with chronic illnesses.


In today’s fast-paced world, tiredness and fatigue are increasingly common problems. According to the United States Centers for Disease Control and Prevention (CDC), around 15.3 percent of American women and 10.1 percent of American men regularly feel very tired or exhausted. If a physician rules out medical conditions as the source of the problem, other possible causes can include insufficient sleep, a lack of exercise, and a poor diet resulting in micronutrient deficiencies.

Chronic fatigue following viral infection is also common. A systematic review published in the journal Nutrients in 2021 considered the feasibility of using high-dose intravenous (IV) vitamin C in the treatment of post-viral fatigue and so-called ‘long COVID’. Reviewing 9 clinical studies involving a total of 720 participants, the authors found that treatment with vitamin C resulted in a significant reduction in fatigue. Other symptoms such as sleep disturbances, lack of concentration, depression, and pain were also frequently alleviated. Noting that vitamin C deficiency has been demonstrated in COVID-19 and other acute severe infections, the authors suggest that high-dose IV administration of this vital nutrient may be a suitable treatment option for patients afflicted with these conditions.

Supplementing with the key micronutrient coenzyme Q10 (CoQ10) has also been shown to be helpful in alleviating fatigue. A meta-analysis of 13 randomized controlled trials published in 2022 confirmed that CoQ10 is an effective and safe supplement for reducing fatigue symptoms. The researchers found that increases in the daily dose and treatment duration of CoQ10 supplementation were correlated with greater fatigue reduction.

Research clearly shows that daily intake of a synergistically designed multi-micronutrient supplement can help prevent micronutrient deficiencies and optimize your energy levels. To read Dr. Rath’s recommendations for daily micronutrient supplementation, see this page on our website.